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Product Infomation
Product NameChlorothiazide
CAS No.

58-94-6

Molecular Weight

295.72

FormulaC₇H₆ClN₃O₄S₂
SMILES

O=S(C1=C(Cl)C=C(C2=C1)N=CNS2(=O)=O)(N)=O

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Product description

Description

Chlorothiazide is a diuretic and antihypertensive. (IC50=3.8 mM) Target: Others Chlorothiazide sodium (Diuril) is a diuretic used within the hospital setting or for personal use to manage excess fluid associated with congestive heart failure. It is also used as an antihypertensive. Most often taken in pill form, it is usually taken orally once or twice a day. In the ICU setting, chlorothiazide is given to diurese a patient in addition to furosemide (Lasix). Working in a separate mechanism than furosemide, and absorbed enterically as a reconstituted suspension administered through a nasogastric tube (NG tube), the two drugs potentiate one another.


IC50 & Target

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In Vitro

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Powder-20°C3 years

4°C2 years
In solvent-80°C6 months

-20°C1 month







Peferences:

[1]. Pogacar PR, et al. Management of central diabetes insipidus in infancy with low renal solute load formula and chlorothiazide. Curr Opin Pediatr. 2000 Aug;12(4):405-11.